BMI1 Antikörper (AA 142-326) (CF®405S)

Produktnummer ABIN7650080

Der Maus Monoklonal Anti-BMI1 Antikörper wurde für WB, IHC, IF und IHC (fp) validiert. Er ist geeignet, BMI1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für BMI1 Antikörper (AA 142-326) (CF®405S) (ABIN7650080)

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BMI1 Antikörper ist konjugiert mit CF®405S

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: BMI1-2823

Produktdetails anti-BMI1 Antikörper (CF®405S)

Bindungsspezifität: AA 142-326

Verwendungszweck: BMI1 (Oncogene and Stem Cell Marker)(BMI1/2823), CF405S conjugate

Produktmerkmale: The B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) is a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (around aa 142-326) of human BMI1 protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: HeLa or Jurkat cells. Colon Carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu BMI1

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Andere Bezeichnung: BMI1

Hintergrund:

Synonyms: BMI1, Polycomb complex protein BMI1, B lymphoma Mo MLV insertion region 1 homolog, BMI1 polycomb ring finger oncogene, Polycomb group ring finger 4, RING finger protein 51

Gene Symbol: BMI1

Molekulargewicht: ~41 kDa

Gen-ID: 648

UniProt: P35226

Pathways: Zellzyklus, Autophagie